Didelis mineralų kiekis kraujyje gali sukelti inkstų akmenų susidarymą. Dietos problemos, didžiulis vitamino D kiekis, medžiagų apykaitos sutrikimai ir žarnyno šuntavimo operacijos gali padidinti kalcio oksalato kiekį šlapime. Kalcio akmenys taip pat susidaro dėl kalcio fosfato.
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